I recently had someone who I followed on twitter send me a direct message and then contact me on Skype to figure out who I was/where I followed them from.  Now, I was not exactly sure the answer to any of those questions, but soon after, I realized that I had met one of the most amazingly caring people on twitter thus far.  This guy actually listened, and we talked for over an hour and a half tonight.  It was amazing to see such a connection can be made over twitter, something that lets you type so little, but helps you express so much.